Pseudogene HSPA7 is a poor prognostic biomarker in Kidney Renal Clear Cell Carcinoma (KIRC) and correlated with immune infiltrates

Abstract Background Pseudogenes played important roles in tumorigenesis, while there are nearly no reports about the expression and of HSPA7 cancer. Methods Firstly, we used Logistic regression, KS test, GEPIA database, UALCAN database qRT-PCR to analyze level KIRC, then Cox regression Kaplan–Meier curve overall survival (OS) KIRC patients with different Clinico-pathological parameters. Thirdly, multivariate analysis influencing factors compare correlation between clinical Finally, multi-GSEA Tumor Immunoassay Resource (TIMER) explore functional role Results The is highly expressed tumor tissues, its related clinico-pathological features patients. GSEA displayed high were several tumor-related immune-related pathways. With TIMER showed that levels correlated CD4 + T cells, neutrophils Dendritic Cell. Conclusions Our study very progression may act as a poor prognostic biomarker for by modulating immune infiltrating cells.